Dandruff and an itchy scalp can be more than just cosmetic — they’re often linked to yeast (Malassezia), seborrheic dermatitis, dryness, or irritation. Medicated shampoos with anti-fungal and anti-itch ingredients can help control flakiness and discomfort.
Here’s a list of the top 10 medicated shampoos available in India, with key benefits and who they’re best suited for.
The best medicated shampoos target the root causes by using ingredients like:
Zinc pyrithione (ZPTO): anti-fungal and antibacterial
Ketoconazole: stronger anti-fungal action
Coal tar: slows skin cell turnover (for severe scaling)
Salicylic acid: helps exfoliate flakes
Selenium sulfide: reduces scalp oil & yeast growth
Many products combine soothing actives (e.g., aloe vera, tea tree) with medicated actives for comfort.
| Shampoo | Key actives | Ideal for | Best use |
|---|---|---|---|
| Nizoral Anti-Dandruff Shampoo | Ketoconazole 2% | stubborn flaking | 1–2×/week deep cleanse |
| Selsun Blue Medicated Shampoo | Selenium sulfide | severe scalp itch | weekly use |
| Head & Shoulders Anti-Dandruff Shampoo | Zinc pyrithione | mild/moderate dandruff | daily to alternate days |
| Dove Dandruff Care Shampoo | Pyrithione zinc + Nutri-Essence | itchy scalp + dryness | regular use |
| Clinic Plus Anti-Dandruff Shampoo | Zinc pyrithione | budget + routine control | everyday mild control |
| Scalpe Pro Anti-Dandruff Shampoo | Zinc pyrithione + Tea tree | itchy scalp + soothing | alternate days |
| Itch Guru Antidandruff Shampoo | Climbazole + Salicylic acid | flake control + exfoliate | weekly to 2×/week |
| Sebamed Anti-Dandruff Shampoo | Piroctone olamine | sensitive scalp | gentle daily use |
| Nivea Anti-Dandruff Shampoo | Zinc pyrithione + hydra agents | dry/flaky scalp | daily/alternate days |
| The Body Shop Ginger Scalp Shampoo | Ginger + zinc | soothing + mild control | regular use |
Best for: stubborn or persistent dandruff
Key active: Ketoconazole 2% — powerful anti-fungal action for moderate to severe flaking.
Why it’s a top pick: Ketoconazole is often recommended by dermatologists when zinc pyrithione alone isn’t enough.
Usage tip: Use once or twice a week — too frequent use can dry the scalp.
Best for: severe scalp itch and heavy scale
Key active: Selenium sulfide — reduces yeast and scalp oil buildup.
Why it works: Good if flaking comes with heavy itching or uneven patches.
User note: A small amount can help go a long way.
Best for: everyday dandruff control
Key active: Zinc pyrithione — widely used and effective antifungal.
Extras: Often has conditioning blends, making hair softer as it treats.
Use frequency: Daily to alternate days depending on dryness/greasiness.
Best for: itchy scalp with dryness
Key actives: Pyrithione zinc + nourishing essence
Why it’s gentle: Combines medicated benefit with Dove’s signature mildness — useful if your scalp is dry and itchy.
Best for: budget-friendly routine management
Key active: Zinc pyrithione
Why we like it: Simple formulation and easy on the pocket, while giving day-to-day flake control.
Best for: mild dandruff and regular upkeep.
Best for: itchy scalp with soothing needs
Key actives: Zinc pyrithione + Tea tree oil
Why it’s worth it: Tea tree lends a calming feel while zinc tackles fungi. Good if itching is your main complaint.
Best for: flaky scaling + scalp buildup
Key actives: Climbazole + Salicylic acid
Why it’s effective: Climbazole targets fungi while salicylic acid loosens flakes — helpful for thick buildup.
Use frequency: 1–2×/week.
Best for: sensitive scalp
Key active: Piroctone olamine — gentler anti-fungal with less irritation tendency.
Why it’s gentle: Sebamed’s pH balancing helps sensitive scalps stay calm while treating flakes.
Best for: dry or itchy scalp plus conditioning
Key actives: Zinc pyrithione + hydrating agents
Why it’s nice: Balances treatment with moisture — good if your hair gets dry with medicated shampoos.
Best for: soothing + mild flake control
Key botanical: Ginger extract + zinc
Why it’s unique: Herbal soothing + anti-dandruff action makes it better for itch + irritation.
Wet hair thoroughly
Apply scalp-focused lather, let sit 2–3 minutes
Rinse well
Follow with conditioner on lengths (avoid scalp if very oily)
Frequency guideline
Daily to alternate days: mild dandruff (Head & Shoulders / Nivea)
Weekly to 2×/week: strong medicated formulas (Nizoral, Itch Guru)
Sensitive scalps: choose gentler medicated options, don’t over-wash
Too much medicated shampoo can dry the scalp and worsen itching.
If you have a sensitive scalp, test behind your ear before full use.
Light scalp oils can help with dryness, but avoid heavy oils on antifungal days.
Advanced note: If itching persists for 3+ weeks with medicated products, consider seeing a dermatologist — persistent seborrheic dermatitis or psoriasis may need prescription care.
Compare final payable on Amazon + Flipkart + brand site
Stack: sale price → Couponlap coupon → bank/UPI offer → cashback
Bulk packs (2–3 bottles) are usually better value for regular use
CTA: If your scalp is itchy and constantly flaky, start with a weekly medicated shampoo (like ketoconazole or climbazole) before adding daily routine options.
1) How soon do medicated shampoos work for dandruff?
Many show noticeable flake reduction in 1–2 weeks with consistent use.
2) Can I use medicated shampoo daily?
For mild formulas, yes. Strong medicated ones are often used weekly or alternate days.
3) Will medicated shampoo make hair dry?
Some formulas can. Pair with a conditioner on lengths (avoid applying on the scalp if too oily).
4) Are herbal shampoos effective for dandruff?
Herbal options help comfort and mild itch, but severe dandruff often needs medicated actives like zinc pyrithione or ketoconazole.
5) When should I see a dermatologist?
If flakes/itch persist despite medicated shampoo for 3+ weeks, or if you have redness/scaling beyond typical dandruff.